Big Mouth

Andrew Rannells

Matthew MacDell (voice)

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Constance the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Joe Wengert

Ayo Edebiri

Missy Foreman-Greenwald (voice)

June Diane Raphael

Devin (voice)

Richard Kind

Marty Glouberman (voice)

Jessica Chaffin

Shannon Glaser (voice)

Neil Casey

Lars (voice)

Paula Pell

Barbara Glouberman (voice)

Jon Daly

Judd Birch (voice)

Jak Knight

DeVon (voice)

Chelsea Peretti

Monica Foreman-Greenwald (voice)

Seth Morris

Greg Glaser (voice)

Gil Ozeri

Nathan Fillion

Nathan Fillion (voice)

Kat Dennings

Leah Birch (voice)

Gina Rodriguez

Gina Alvarez (voice)

David Thewlis

Shame Wizard (voice)

Thandiwe Newton

Brandon Kyle Goodman

Walter the Lovebug (voice)

Maria Bamford

Heather Lawless

Jenna Bilzerian (voice)

Mark Duplass

Val Bilzerian (voice)

Whitmer Thomas

Paul Scheer

Kurt Bilzerian (voice)

Ali Wong

Ali (voice)

Zachary Quinto

Aiden (voice)

Stephanie Beatriz

Chloe Fineman

Rob Huebel

Mr. Lizer (voice)

Natasha Lyonne

Suzette (voice)

Gary Cole

Jean Smart

Depression Kitty (voice)

Jack McBrayer

Pubic Hair #1 (voice)

John Gemberling

Tyler the Hormone Monster (voice)

Craig Robinson

Pubic Hair #2 (voice)

Michaela Watkins

Cantor Dina Reznick (voice)

Fran Gillespie

(voice)

Kristen Bell

Pam the Pillow (voice)

Zach Woods

Rosa Salazar

Ms. Benitez (voice)

Quinta Brunson

Quinta (voice)

Ayden Mayeri

Gabrielle / Sad Boy #2 (voice)

Andy Daly

Dr. Wendy Engle / Motel Pillow #1 (voice)

Bobby Cannavale

Nick's Agent (voice)

John Oliver

Harry (voice)

Seth Rogen

Seth Goldberg (voice)

Julie White

Kimberly (voice)

Sterling K. Brown

Michael Angelo (voice)

Kristen Wiig

Jessi's Vagina (voice)

Lena Waithe

Lena (voice)

Megan Thee Stallion

Megan the(e?) Hormone Monstress (voice)

Patrick Page

Dread (voice)

Carlos Alazraqui

Gustavo (voice)

Julie Klausner

Cherry Marashina (voice)

Chris Redd

(voice)

Josie Totah

Natalie (voice)

Joel Kim Booster

Charles Lu (voice)

Judd Hirsch

Lewis Glouberman (voice)

Beck Bennett

Owen (voice)

Billy Porter

Ocean (voice)

Keke Palmer

Aidy Bryant

Emmy (voice)

Rosie Perez

Petra (voice)

Mitra Jouhari

Juliet Mills

Pamela Adlon

Sonya the Lovebug (voice)

Jon Hamm

Scallops (voice)

Jon Gabrus

Movie Theater Customer (voice)

Anna Graves

Mrs. Albert (voice)

Nasim Pedrad

Fatima (voice)

Mae Whitman

Tallulah Levine (voice)

Philip Quinaz

Tanya Alvarez (voice)

Harvey Fierstein

Older Guy Town Resident (voice)

Jerry Minor

Man #3 / Singing Fish (voice)

Piotr Michael

Siamese Twin #2 (voice)

Martin Short

Gordie (voice)

David Cross

Skip Glouberman (voice)

Carol Kane

Menopause Banshee / Old Woman (voice)

Tawny Newsome

(voice)

Retta

Duke's Mother (voice)

Wanda Sykes

Ghost of Harriet Tubman (voice)

Jaboukie Young-White

(voice)

Rob Riggle

Sgt. Adderall (voice)

Bobby Berk

Bobby Berk (voice)

Karamo Brown

Karamo Brown (voice)

Tan France

Tan France (voice)

Antoni Porowski

Antoni Porowski (voice)

Jonathan Van Ness

Jonathan Van Ness (voice)

Anna Konkle

Izzy (voice)

Maya Erskine

Misha (voice)

Alia Shawkat

Roland (voice)

Paul Giamatti

Andrew’s Shit (voice)

Adam Scott

Mr. Keating (voice)

Hugh Jackman

himself (voice)

Kumail Nanjiani

himself (voice)

Jemaine Clement

Simon Sex (voice)

Kristen Schaal

Bernie Sanders (voice)

Somali Rose

Missy’s Overalls

Lupita Nyong'o

Asha (voice)

Miranda Tapsell

Kara (voice)

Lin-Manuel Miranda

Puerto Rican Pubic Hair (voice)

Randall Park

Pete Doheny (voice)

Maitreyi Ramakrishnan

Marissa (voice)

Ava Lalezarzadeh

Nazanin (voice)

Don Cheadle

Don Cheadle (voice)

Padma Lakshmi

Priya (voice)

Zach Galifianakis

Gratitoad (voice)

Jeff Goldblum

The Apple Brooch

Steve Buscemi

Skyla I'Lece

Larry Owens

Holly Hunter

James III

Cynthia Erivo

Andrew Goldberg