Velma

Mindy Kaling

Velma (voice)

Constance Wu

Daphne (voice)

Sam Richardson

Norville (voice)

Glenn Howerton

Fred (voice)

Jane Lynch

Donna (voice)

Sarayu Blue

Diya (voice)

Karl-Anthony Towns

Handsome Jock (voice)

'Weird Al' Yankovic

Dandruff Tuba (voice)

Natalia del Riego

Becca (voice)

Nicole Byer

Blythe (voice)

Cherry Jones

Victoria (voice)

Ken Leung

Darren (voice)

Frank Welker

William (voice)

James Adomian

Thespian (voice)

Gary Cole

Lamont / General Meeting (voice), Lamont (voice)

Roger Craig Smith

Stoner (voice)

Themo Melikidze

Skinhead (voice)

Dimitry Rozental

Russian Soldier (voice)

Jim Rash

Mayor Dave (voice)

Melissa Fumero

Sophie / Uncle Scoobi (voice), Sophie (voice)

Wanda Sykes

Krista (voice), Linda (voice)

Russell Peters

Aman (voice), Aman (voice

Debby Ryan

Donna (voice), Krista (voice)

Tiana Camacho

Kimmy (voice)

Ming-Na Wen

Carroll (voice)

Yvonne Orji

Gigi (voice), Sammy (voice)

Fortune Feimster

Olive (voice), Olive / Pim (voice)

Shay Mitchell

Brenda (voice)

Kimberly Brooks

Cool Edy Girl (voice), Susan (voice)

Kulap Vilaysack

Lola (voice)

Stephen Root

Chief Cogburn / Merie Cogburn (voice), Chief Cogburn (voice), Merie Cogburn (voice)

Chris Schleicher

Male Nurse (voice)

Akshara Sekar

Influencer (voice)

Gary Anthony Williams

Sgt. Gigisfather / Private Eye (voice), Don (voice)

Jennifer Hale

Thorn (voice)

Kari Wahlgren

Amanda / Maxine / Moira (voice), Mary Louis (voice), Evelyn / Female News Anchor (voice), Evelyn (voice), Seductive Woman (voice), Acne Saxophone (voice), Evelyn / Paramedic (voice), Female News Anchor (voice), Chestiny (voice), Moira (voice), Amanda (voice), Anchor Woman (voice)

Ed Weeks

Mr. S (voice)

Andia Winslow

Gigi (voice)

Andrew Morgado

Fro Yo (voice), Fro Yo / Jerry Brown (voice), Normal Coroner (voice), Commanding Officer (voice), Froyo (voice)

Neil deGrasse Tyson

Neil deGrasse Tyson (voice)

Yoshi Amao

Japanese Dad (voice)

Alpha Takahashi

Japanese Mom (voice)

Vanessa Williams

Dr. Perdue (voice)

Piotr Michael

Father O'Rourke (voice), Casey Kasem (voice), Whisper / Voice (voice), Deputy Greg / Pencil (voice), Creepy Coroner (voice), Board Member / Lion Tamer (voice)

June Squibb

Older Woman (voice)

Carolyn Hennesy

Elizabeth (voice)

Jason Mantzoukas

Scrappy (voice)

Winsome Brown

Female Librarian (voice)

Sara Ramirez

Amber (voice)

Nicholas Braun

Black Knight / Geoff (voice)

Richard Kind

Richard Kind (voice)

Saweetie

Saweetie (voice)